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Social and demographic change has shaken the foundation for some of what it means to be American. It has set the backdrop of this campaign in ways that were predictable and completely surprising.

The idea for a cancer "moonshot" did not originate with President Biden. Medical philanthropist Mary Lasker gets much of the credit. She was the first to push the idea 50 years ago.

Prison rules created to control men often don't work well for women, who come with different histories and experiences. "Gender-responsive corrections" aims to treat women based on these differences.

Puerto Rico, the nation's sixth-largest school district, is in crisis. It's both uniquely vulnerable to natural disasters and unusually ill-equipped to help children recover from them.

Last year, our tech reporters looked ahead to developments dealing with anticipatory computing, data breaches and Apple. Now as 2015 ends, they consider what has changed.

Two years ago Pakistan's Punjab province was hit with one of the world's worst dengue outbreaks. This year the number of recorded cases has plummeted. Many leaders credit a mobile phone app that tracks mosquito populations and city workers' efforts to contain them.

The CD is just the latest musical format to rise and fall in roughly the same 30-year cycle.

Sheriff deputies in Polk County said they encountered a massive gunfight Sunday with a suspect in full body armor. Authorities said the suspect, who is now hospitalized, was "ready for battle."

As of Oct. 1, some first-class mail has been delivered more slowly. Some say between that and recent price increases, it spells trouble for the agency.

Many Palestinian stabbing attacks against Israelis have come from the West Bank city of Hebron. One activist is urging his fellow Palestinians to find other ways to oppose Israel.

NPR's Sarah McCammon talks with Elisa Gould, a senior economist at the Economic Policy Institute, about the latest monthly jobs report published Friday.

Science shows the value of boosters against COVID, but many vaccinated people haven't gotten the shot. About 40% of people who are eligible have been boosted, which could be bad if COVID surges again.

Scientists now know that the potency of the booster shot wanes quickly after about three months. We look at the latest research on a fourth shot.

When the Simpsons first aired in 1989, the show depicted a typical American middle-class family. NPR's The Indicator from Planet Money investigates whether that remains true in 2022.

A day after the Senate confirmed Judge Ketanji Brown Jackson as the first Black woman on the Supreme Court, she spoke at the White House with President Biden and Vice President Harris

The vaccines now in use are based on the form of the virus that circulated at the beginning of the pandemic and are less effective against the omicron variant. New options are in the works.

A jury in Brunswick, Ga., unanimously found defendants Travis McMichael, his father Greg McMichael, and their neighbor William "Roddie" Bryan guilty on all counts in a federal hate crimes trial.

While governors in several states are moving to lift mask mandates, the Centers for Disease Control and Prevention today reiterated that it's not changing it's mask guidance.

A 17-year-old in California who got curious about the impact of AI on typical teen jobs. She embarked on an ambitious economic research project and shared her findings with us.

Adrian Florido speaks with Joshua Benton of the Nieman Journalism Lab at Harvard University about the increasing number of news deserts.